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Optune Lua—For unresectable, locally advanced or metastatic, MALIGNANT PLEURAL MESOTHELIOMA (MPM)1


Consider Optune Lua for your next MPM patient

STELLAR Clinical Results: Patients who used Optune Lua first line together with pemetrexed + cisplatin or carboplatin achieved 18.2 months median OS with no added systemic AEs1,2

STELLAR: Primary endpoint: 18.2 months. Median OS (95% CI 12.1-25.8). In a population that includes patients with epithelioid and nonepithelioid histologies.

Optune Lua approval was based on the STELLAR study: a prospective, multicenter, single-arm, phase 2 study designed to study the safety and efficacy of Optune Lua and pemetrexed + cisplatin or carboplatin first line in patients with unresectable, locally advanced or metastatic, MPM.1,2

No systemic AEs were considered to be related to the use of Optune Lua

  • The only AE attributed to Optune Lua use was skin irritation (71% of patients); 66% mild-to-moderate and 5% severe. No SAEs were considered related to device use1,2
View STELLAR efficacy outcomes View STELLAR safety results
The second-generation Optune Lua system
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AEs, adverse events; SAEs, serious adverse events.

References: 1. Optune Lua. Instructions for Use for Unresectable Malignant Pleural Mesothelioma. Novocure; 2021. 2. Ceresoli GL, Aerts JG, Dziadziuszko R, et al. Tumour Treating Fields in combination with pemetrexed and cisplatin or carboplatin as first-line treatment for unresectable malignant pleural mesothelioma (STELLAR): a multicentre, single-arm phase 2 trial. Lancet Oncol. 2019;20(12):1702-1709 doi:10.1016/S1470-2045(19)30532-7 3. Optune Lua. Patient Information and Operation Manual for Unresectable Malignant Pleural Mesothelioma. Novocure; 2021.

Next: FDA approval for unresectable MPM
Indications For Use
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The Optune Lua System is indicated for the treatment of adult patients with unresect…


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